Disease: Cocaine-Related Disorders
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TACR3 P29371 tachykinin receptor 3 G-protein coupled receptor 1.8E-17 0.553 0.769
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
NPS P0C0P6 neuropeptide S 1.4E-04 0.619 0.615
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
NPY2R P49146 neuropeptide Y receptor Y2 G-protein coupled receptor 3.6E-02 0.612 0.577
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
CARTPT Q16568 CART prepropeptide 9.4E-02 0.576 0.692
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
CRHBP P24387 corticotropin releasing hormone binding protein Signaling 0.21 0.659 0.500
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
ARC Q7LC44 activity regulated cytoskeleton associated protein 0.59 0.573 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
GABRG2 P18507 gamma-aminobutyric acid type A receptor subunit gamma2 Ion channel 0.74 0.548 0.654