Disease: Pregnancy associated hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
CCL20 P78556 C-C motif chemokine ligand 20 Signaling 2.4E-04 0.474 0.846
CYP3A5 P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 6.3E-17 0.511 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
LEP P41159 leptin 0.46 0.349 0.846
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962