Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CERS3 Q8IU89 ceramide synthase 3 5.7E-03 0.705 0.308
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769
DMD P11532 dystrophin 1.00 0.423 0.923
DSC2 Q02487 desmocollin 2 Cell adhesion 5.2E-08 0.610 0.538
DSC3 Q14574 desmocollin 3 Cell adhesion 2.3E-21 0.570 0.808
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
GJB4 Q9NTQ9 gap junction protein beta 4 Cell-cell junction 5.5E-04 0.691 0.462
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
JUP P14923 junction plakoglobin 8.0E-04 0.628 0.500
KDSR Q06136 3-ketodihydrosphingosine reductase 0.12 0.674 0.538
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923