Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
FIG4 | Q92562 | FIG4 phosphoinositide 5-phosphatase | 2.3E-34 | 0.551 | 0.731 | |
SCN8A | Q9UQD0 | sodium voltage-gated channel alpha subunit 8 | Ion channel | 1.00 | 0.510 | 0.731 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
PIGL | Q9Y2B2 | phosphatidylinositol glycan anchor biosynthesis class L | 6.2E-09 | 0.581 | 0.731 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
WASHC5 | Q12768 | WASH complex subunit 5 | Transporter | 8.3E-18 | 0.572 | 0.615 |
NEK1 | Q96PY6 | NIMA related kinase 1 | Kinase | 1.9E-25 | 0.575 | 0.769 |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
SPG11 | Q96JI7 | SPG11 vesicle trafficking associated, spatacsin | 1.6E-39 | 0.576 | 0.538 | |
GLE1 | Q53GS7 | GLE1 RNA export mediator | Transporter | 2.1E-10 | 0.628 | 0.577 |
CHCHD10 | Q8WYQ3 | coiled-coil-helix-coiled-coil-helix domain containing 10 | 5.4E-06 | 0.623 | 0.462 | |
NRXN1 | P58400 Q9ULB1 | neurexin 1 | 1.00 | 0.581 | 0.692 | |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
GRIP1 | Q9Y3R0 | glutamate receptor interacting protein 1 | 0.51 | 0.581 | 0.769 | |
HNRNPA1 | P09651 | heterogeneous nuclear ribonucleoprotein A1 | 1.00 | 0.529 | 0.885 | |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
DCTN1 | Q14203 | dynactin subunit 1 | Chaperone | 8.4E-02 | 0.597 | 0.500 |
SETX | Q7Z333 | senataxin | Enzyme | 0.95 | 0.570 | 0.731 |
ATXN3 | P54252 | ataxin 3 | Enzyme | 0.11 | 0.521 | 0.808 |
KIF5A | Q12840 | kinesin family member 5A | Cellular structure | 1.00 | 0.593 | 0.731 |