Disease: Agenesis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FOXC1 Q12948 forkhead box C1 Transcription factor 0.95 0.483 0.846
FOXE1 O00358 forkhead box E1 Transcription factor 0.79 0.573 0.731
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
OTX2 P32243 orthodenticle homeobox 2 Transcription factor 0.92 0.514 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
ZEB1 P37275 zinc finger E-box binding homeobox 1 Transcription factor 0.97 0.442 0.808
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
GDF11 O95390 growth differentiation factor 11 Signaling 0.98 0.584 0.692
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808