Disease: Malignant transformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTCH1 Q13635 patched 1 1.00 0.398 0.885
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885
GSTK1 Q9Y2Q3 glutathione S-transferase kappa 1 1.9E-06 0.412 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
S100A1 P23297 S100 calcium binding protein A1 Calcium-binding protein 6.0E-03 0.421 0.846
MIR34A microRNA 34a 0.421 0.846
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885