Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
ZMPSTE24 | O75844 | zinc metallopeptidase STE24 | Enzyme | 8.9E-16 | 0.517 | 0.731 |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
PMM2 | O15305 | phosphomannomutase 2 | Enzyme | 1.4E-17 | 0.535 | 0.769 |
GATA4 | P43694 | GATA binding protein 4 | 0.49 | 0.458 | 0.846 | |
TET2 | Q6N021 | tet methylcytosine dioxygenase 2 | 4.3E-54 | 0.458 | 0.808 | |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
IDUA | P35475 | alpha-L-iduronidase | Enzyme | 3.8E-13 | 0.499 | 0.846 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
ENPP1 | P22413 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | Enzyme | 5.0E-08 | 0.498 | 0.808 |
SCN5A | Q14524 | sodium voltage-gated channel alpha subunit 5 | Ion channel | 0.91 | 0.513 | 0.654 |
XYLT1 | Q86Y38 | xylosyltransferase 1 | 0.92 | 0.581 | 0.731 | |
GATA6 | Q92908 | GATA binding protein 6 | 1.00 | 0.478 | 0.808 | |
MPL | P40238 | MPL proto-oncogene, thrombopoietin receptor | Receptor | 4.1E-09 | 0.510 | 0.692 |
HLA-DPB1 | P04440 | major histocompatibility complex, class II, DP beta 1 | Immune response | 5.3E-10 | 0.453 | 0.923 |
PIGA | P37287 | phosphatidylinositol glycan anchor biosynthesis class A | 0.96 | 0.575 | 0.654 | |
ABCC6 | O95255 | ATP binding cassette subfamily C member 6 | Transporter | 5.6E-35 | 0.540 | 0.654 |
GLA | P06280 | galactosidase alpha | 1.00 | 0.537 | 0.769 | |
HLA-DPA1 | P20036 | major histocompatibility complex, class II, DP alpha 1 | Immune response | 2.5E-06 | 0.552 | 0.846 |
CYP27A1 | Q02318 | cytochrome P450 family 27 subfamily A member 1 | Enzyme | 5.3E-19 | 0.538 | 0.731 |
APOB | P04114 | apolipoprotein B | 1.9E-16 | 0.453 | 0.808 | |
XYLT2 | Q9H1B5 | xylosyltransferase 2 | 0.93 | 0.566 | 0.808 | |
PRTN3 | P24158 | proteinase 3 | Enzyme | 3.8E-05 | 0.503 | 0.808 |