Disease: Premature coronary artery atherosclerosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC6 O95255 ATP binding cassette subfamily C member 6 Transporter 5.6E-35 0.540 0.654
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LDLRAP1 Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 6.5E-06 0.641 0.538
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LMNA P02545 lamin A/C 1.00 0.384 0.885
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
PLA2G1B P04054 phospholipase A2 group IB Enzyme 1.0E-10 0.468 0.846
PLA2G2A P14555 phospholipase A2 group IIA Enzyme 9.7E-02 0.488 0.808