Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
FOLH1 | Q04609 | folate hydrolase 1 | Enzyme | 6.2E-09 | 0.453 | 0.885 |
MMP12 | P39900 | matrix metallopeptidase 12 | Enzyme | 0.484 | 0.885 | |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
CCN2 | P29279 | cellular communication network factor 2 | Signaling | 5.0E-04 | 0.399 | 0.846 |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
SOX9 | P48436 | SRY-box transcription factor 9 | 1.00 | 0.419 | 0.846 | |
DES | P17661 | desmin | 8.8E-03 | 0.460 | 0.846 | |
SLPI | P03973 | secretory leukocyte peptidase inhibitor | Enzyme modulator | 9.0E-04 | 0.449 | 0.846 |