Disease: Mixed anxiety and depressive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808
LEP P41159 leptin 0.46 0.349 0.846
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NUCB2 P80303 nucleobindin 2 Calcium-binding protein 2.0E-10 0.540 0.731
OR2AG1 Q9H205 olfactory receptor family 2 subfamily AG member 1 (gene/pseudogene) G-protein coupled receptor 3.1E-11 0.582 0.808
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
SCD O00767 stearoyl-CoA desaturase 0.97 0.490 0.808
SCLY Q96I15 selenocysteine lyase Enzyme 2.3E-09 0.530 0.731
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808