Disease: Idiopathic pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SAMHD1 Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 6.5E-13 0.547 0.769
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885
IL23A Q9NPF7 interleukin 23 subunit alpha Signaling 0.36 0.415 0.846
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885
MAP1LC3B Q9GZQ8 microtubule associated protein 1 light chain 3 beta Cellular structure 1.9E-03 0.506 0.846
FSD1L Q9BXM9 fibronectin type III and SPRY domain containing 1 like 0.23 0.488 0.808
FSD1 Q9BTV5 fibronectin type III and SPRY domain containing 1 0.25 0.486 0.808
CHDH Q8NE62 choline dehydrogenase Enzyme 1.7E-06 0.529 0.769
SLC25A24 Q6NUK1 solute carrier family 25 member 24 Transporter 3.4E-12 0.575 0.731
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
HDAC1 Q13547 histone deacetylase 1 Epigenetic regulator 0.61 0.460 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
TAGLN Q01995 transgelin Cellular structure 8.5E-02 0.540 0.692
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923