Disease: Congenital arteriovenous malformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SLPI P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 9.0E-04 0.449 0.846
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
RBBP8 Q99708 RB binding protein 8, endonuclease Transcription factor 3.1E-12 0.584 0.808
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885
PDGFD Q9GZP0 platelet derived growth factor D Signaling 1.7E-03 0.579 0.538
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846
PCYT1A P49585 phosphate cytidylyltransferase 1, choline, alpha 2.0E-05 0.485 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MIR195 microRNA 195 0.496 0.769
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885