Disease: Marfan Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
ELN P15502 elastin 2.1E-14 0.415 0.885
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TAGLN Q01995 transgelin Cellular structure 8.5E-02 0.540 0.692
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
CDH5 P33151 cadherin 5 0.51 0.561 0.692
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962