Disease: Scleroderma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LTB4R Q15722 leukotriene B4 receptor G-protein coupled receptor 0.12 0.576 0.692
CRISP2 P16562 cysteine rich secretory protein 2 Immune response 1.4E-12 0.512 0.769
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
SPZ1 Q9BXG8 spermatogenic leucine zipper 1 0.507 0.769
PRSS55 Q6UWB4 serine protease 55 Enzyme 3.2E-11 0.513 0.769
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
COMP P49747 cartilage oligomeric matrix protein 1.3E-09 0.503 0.808
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MIR29A microRNA 29a 0.459 0.808
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
TNC P24821 tenascin C 1.3E-07 0.433 0.846
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
LOX P28300 lysyl oxidase 0.99 0.447 0.846
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MIR21 microRNA 21 0.363 0.846
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885