Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ZIC3 O60481 Zic family member 3 Transcription factor 0.92 0.587 0.423
TSHZ1 Q6ZSZ6 teashirt zinc finger homeobox 1 Transcription factor 1.00 0.569 0.731
OSR1 Q8TAX0 odd-skipped related transcription factor 1 Transcription factor 0.86 0.603 0.615
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
ACVRL1 P37023 activin A receptor like type 1 Kinase 9.7E-04 0.493 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885