Disease: Idiopathic pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SLPI P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 9.0E-04 0.449 0.846
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
SAMHD1 Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 6.5E-13 0.547 0.769
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
PCYT1A P49585 phosphate cytidylyltransferase 1, choline, alpha 2.0E-05 0.485 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MSC O60682 musculin 2.5E-02 0.475 0.846
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923