Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
HLA-DQB1 | P01920 | major histocompatibility complex, class II, DQ beta 1 | Immune response | 8.9E-03 | 0.407 | 0.885 |
COL1A1 | P02452 | collagen type I alpha 1 chain | 1.00 | 0.430 | 0.808 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
COX1 | P00395 | cytochrome c oxidase subunit I | Enzyme | 0.441 | 0.885 | |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
GJB2 | P29033 | gap junction protein beta 2 | Cell-cell junction | 6.6E-16 | 0.441 | 0.846 |
PLAT | P00750 | plasminogen activator, tissue type | Enzyme | 5.7E-05 | 0.445 | 0.885 |
TCF4 | P15884 | transcription factor 4 | Transcription factor | 1.00 | 0.464 | 0.846 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
EHMT1 | Q9H9B1 | euchromatic histone lysine methyltransferase 1 | Epigenetic regulator | 1.00 | 0.460 | 0.808 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
DNMT3B | Q9UBC3 | DNA methyltransferase 3 beta | 0.20 | 0.453 | 0.846 | |
S100A4 | P26447 | S100 calcium binding protein A4 | Calcium-binding protein | 6.2E-03 | 0.448 | 0.769 |