Disease: Degenerative polyarthritis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
IL2 P60568 interleukin 2 0.48 0.336 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
LEP P41159 leptin 0.46 0.349 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962