Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FGF1 P05230 fibroblast growth factor 1 Signaling 0.44 0.507 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
SPRED2 Q7Z698 sprouty related EVH1 domain containing 2 Receptor 2.9E-07 0.711 0.577
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808