Disease: Xeroderma Pigmentosum, Complementation Group D
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDA P32320 cytidine deaminase Enzyme 8.1E-03 0.558 0.731
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
MARCHF1 Q8TCQ1 membrane associated ring-CH-type finger 1 8.7E-03 0.540 0.808
MNAT1 P51948 MNAT1 component of CDK activating kinase Enzyme modulator 1.3E-12 0.539 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
NLRP2 Q9NX02 NLR family pyrin domain containing 2 1.4E-38 0.515 0.731
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PPP1R1A Q13522 protein phosphatase 1 regulatory inhibitor subunit 1A Enzyme modulator 2.2E-02 0.559 0.692