Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
PLXNA2 O75051 plexin A2 1.1E-06 0.447 0.808
PYCARD Q9ULZ3 PYD and CARD domain containing Enzyme 2.0E-04 0.457 0.808
TYR P14679 tyrosinase Enzyme 5.0E-32 0.473 0.808
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PCYT1A P49585 phosphate cytidylyltransferase 1, choline, alpha 2.0E-05 0.485 0.885
USP9X Q93008 ubiquitin specific peptidase 9 X-linked 1.00 0.502 0.846