Disease: Fanconi Anemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BIK Q13323 BCL2 interacting killer 5.0E-06 0.653 0.462
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCNB1 P14635 cyclin B1 Enzyme modulator 0.16 0.512 0.731
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CDK1 P06493 cyclin dependent kinase 1 Kinase 0.99 0.482 0.808
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
DHFR P00374 dihydrofolate reductase Enzyme 3.4E-02 0.513 0.808
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
EXO1 Q9UQ84 exonuclease 1 Enzyme 8.1E-13 0.578 0.692
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731