Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AAGAB | Q6PD74 | alpha and gamma adaptin binding protein | 3.9E-07 | 0.695 | 0.538 | |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
AKT2 | P31751 | AKT serine/threonine kinase 2 | Kinase | 0.64 | 0.474 | 0.769 |
ALOX5 | P09917 | arachidonate 5-lipoxygenase | Enzyme | 1.2E-06 | 0.447 | 0.885 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
ATR | Q13535 | ATR serine/threonine kinase | Kinase | 3.5E-09 | 0.456 | 0.923 |
BAX | Q07812 | BCL2 associated X, apoptosis regulator | Signaling | 0.32 | 0.417 | 0.885 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
BUB1 | O43683 | BUB1 mitotic checkpoint serine/threonine kinase | Kinase | 4.9E-09 | 0.528 | 0.731 |
CASP1 | P29466 | caspase 1 | Enzyme | 3.5E-05 | 0.413 | 0.885 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CASP8 | Q14790 | caspase 8 | Enzyme | 3.7E-06 | 0.404 | 0.923 |
CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CD40 | P25942 | CD40 molecule | 0.85 | 0.396 | 0.846 | |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
DPYD | Q12882 | dihydropyrimidine dehydrogenase | Enzyme | 3.4E-22 | 0.493 | 0.846 |
E2F1 | Q01094 | E2F transcription factor 1 | Nucleic acid binding | 0.99 | 0.441 | 0.846 |