Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
ANGPT2 | O15123 | angiopoietin 2 | Signaling | 0.83 | 0.410 | 0.846 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BUB1 | O43683 | BUB1 mitotic checkpoint serine/threonine kinase | Kinase | 4.9E-09 | 0.528 | 0.731 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CASP8 | Q14790 | caspase 8 | Enzyme | 3.7E-06 | 0.404 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CD40 | P25942 | CD40 molecule | 0.85 | 0.396 | 0.846 | |
CD40LG | P29965 | CD40 ligand | Signaling | 0.72 | 0.414 | 0.846 |
CDK1 | P06493 | cyclin dependent kinase 1 | Kinase | 0.99 | 0.482 | 0.808 |
CDKN1A | P38936 | cyclin dependent kinase inhibitor 1A | 1.9E-03 | 0.403 | 0.769 | |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
DHFR | P00374 | dihydrofolate reductase | Enzyme | 3.4E-02 | 0.513 | 0.808 |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ETS1 | P14921 | ETS proto-oncogene 1, transcription factor | Transcription factor | 0.78 | 0.444 | 0.731 |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
FOXO3 | O43524 | forkhead box O3 | 0.99 | 0.431 | 0.808 | |
GABPA | Q06546 | GA binding protein transcription factor subunit alpha | Transcription factor | 1.00 | 0.379 | 0.885 |
H2AX | P16104 | H2A.X variant histone | Nucleic acid binding | 0.18 | 0.484 | 0.808 |