Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
DCN P07585 decorin 0.31 0.457 0.808
EDN3 P14138 endothelin 3 Signaling 2.5E-02 0.608 0.577
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FGF1 P05230 fibroblast growth factor 1 Signaling 0.44 0.507 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NPPC P23582 natriuretic peptide C Signaling 6.1E-02 0.568 0.769
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962