Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
LEP P41159 leptin 0.46 0.349 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
LMNA P02545 lamin A/C 1.00 0.384 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
MIR21 microRNA 21 0.363 0.846
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923