Disease: Mental Retardation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
ALB P02768 albumin Transporter 0.64 0.317 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
DMD P11532 dystrophin 1.00 0.423 0.923
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808