Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
TDO2 P48775 tryptophan 2,3-dioxygenase Enzyme 2.0E-10 0.599 0.654
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
LEP P41159 leptin 0.46 0.349 0.846
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL2 P60568 interleukin 2 0.48 0.336 0.885
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769