Disease: Unipolar Depression
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
TDO2 P48775 tryptophan 2,3-dioxygenase Enzyme 2.0E-10 0.599 0.654
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
RELN P78509 reelin 1.00 0.515 0.731
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
IL6 P05231 interleukin 6 0.32 0.248 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
GLO1 Q04760 glyoxalase I 9.7E-07 0.537 0.769
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885