Disease: Depressive disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
NPAS2 Q99743 neuronal PAS domain protein 2 1.00 0.595 0.654
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
RELN P78509 reelin 1.00 0.515 0.731
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
PDE4A P27815 phosphodiesterase 4A 0.98 0.523 0.846
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
CADM1 Q9BY67 cell adhesion molecule 1 0.66 0.491 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
PDE4B Q07343 phosphodiesterase 4B 0.47 0.566 0.731
LEP P41159 leptin 0.46 0.349 0.846
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962