Disease: Depressive disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
DIXDC1 Q155Q3 DIX domain containing 1 Signaling 7.3E-11 0.647 0.385
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
GABRA3 P34903 gamma-aminobutyric acid type A receptor subunit alpha3 Ion channel 3.9E-02 0.636 0.577
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR1D P28221 5-hydroxytryptamine receptor 1D G-protein coupled receptor 6.4E-04 0.716 0.308
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923