Disease: Depressive disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
CADM1 Q9BY67 cell adhesion molecule 1 0.66 0.491 0.769
NPAS2 Q99743 neuronal PAS domain protein 2 1.00 0.595 0.654
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
DIXDC1 Q155Q3 DIX domain containing 1 Signaling 7.3E-11 0.647 0.385
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
PDE4B Q07343 phosphodiesterase 4B 0.47 0.566 0.731
GLO1 Q04760 glyoxalase I 9.7E-07 0.537 0.769
RELN P78509 reelin 1.00 0.515 0.731
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
ASMT P46597 acetylserotonin O-methyltransferase 1.3E-20 0.691 0.346
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
LEP P41159 leptin 0.46 0.349 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923