Disease: Bipolar Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
INPP1 P49441 inositol polyphosphate-1-phosphatase Enzyme 7.9E-07 0.821 0.192
HTR5A P47898 5-hydroxytryptamine receptor 5A G-protein coupled receptor 6.3E-03 0.716 0.231
RIMS1 Q86UR5 regulating synaptic membrane exocytosis 1 Enzyme modulator 0.99 0.700 0.231
ASMT P46597 acetylserotonin O-methyltransferase 1.3E-20 0.691 0.346
GABRA5 P31644 gamma-aminobutyric acid type A receptor subunit alpha5 Ion channel 0.91 0.621 0.385
NLGN1 Q8N2Q7 neuroligin 1 0.85 0.705 0.385
SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains 2 8.4E-07 0.663 0.385
DIXDC1 Q155Q3 DIX domain containing 1 Signaling 7.3E-11 0.647 0.385
DLX1 P56177 distal-less homeobox 1 Transcription factor 0.96 0.695 0.462
ASTN2 O75129 astrotactin 2 1.00 0.666 0.462
GABRB1 P18505 gamma-aminobutyric acid type A receptor subunit beta1 Ion channel 0.98 0.686 0.500
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
ST8SIA2 Q92186 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 5.8E-02 0.674 0.538
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577
GABRA3 P34903 gamma-aminobutyric acid type A receptor subunit alpha3 Ion channel 3.9E-02 0.636 0.577
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
SLC1A3 P43003 solute carrier family 1 member 3 Transporter 0.99 0.573 0.577
CNTN4 Q8IWV2 contactin 4 Receptor 3.3E-06 0.653 0.577
DAO P14920 D-amino acid oxidase 6.2E-22 0.636 0.615
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
NPAS2 Q99743 neuronal PAS domain protein 2 1.00 0.595 0.654
TDO2 P48775 tryptophan 2,3-dioxygenase Enzyme 2.0E-10 0.599 0.654
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692