Disease: Primary hypogonadism
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AMH P03971 anti-Mullerian hormone 3.4E-12 0.476 0.846
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
DMRT3 Q9NQL9 doublesex and mab-3 related transcription factor 3 6.2E-06 0.653 0.500
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
FANCE Q9HB96 FA complementation group E 1.5E-06 0.553 0.808
FSHB P01225 follicle stimulating hormone subunit beta Signaling 0.34 0.631 0.577
FSHR P23945 follicle stimulating hormone receptor G-protein coupled receptor 1.4E-11 0.539 0.654
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
LEP P41159 leptin 0.46 0.349 0.846
LHCGR P22888 luteinizing hormone/choriogonadotropin receptor G-protein coupled receptor 5.3E-08 0.528 0.692
MAP3K1 Q13233 mitogen-activated protein kinase kinase kinase 1 Kinase 1.00 0.538 0.731
MCM8 Q9UJA3 minichromosome maintenance 8 homologous recombination repair factor Enzyme 1.1E-16 0.678 0.385
NR0B1 P51843 nuclear receptor subfamily 0 group B member 1 Nuclear receptor 0.97 0.494 0.808
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731
SCP2 P22307 sterol carrier protein 2 8.7E-07 0.644 0.500
SLC29A3 Q9BZD2 solute carrier family 29 member 3 Transporter 1.3E-07 0.578 0.769
SOHLH1 Q5JUK2 spermatogenesis and oogenesis specific basic helix-loop-helix 1 2.3E-03 0.705 0.269
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808
VAMP7 P51809 vesicle associated membrane protein 7 Transporter 1.4E-02 0.612 0.577
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808