Disease: Cholestasis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
RDX P35241 radixin Cellular structure 0.85 0.593 0.615
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
FOXA2 Q9Y261 forkhead box A2 Transcription factor 0.74 0.528 0.769
ALB P02768 albumin Transporter 0.64 0.317 0.962
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
FGF19 O95750 fibroblast growth factor 19 Signaling 0.57 0.548 0.615
ONECUT1 Q9UBC0 one cut homeobox 1 Transcription factor 0.52 0.686 0.346
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769