Disease: Cholestasis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
ALB P02768 albumin Transporter 0.64 0.317 0.962
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FGF19 O95750 fibroblast growth factor 19 Signaling 0.57 0.548 0.615
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FOXA2 Q9Y261 forkhead box A2 Transcription factor 0.74 0.528 0.769
GGT1 P19440 gamma-glutamyltransferase 1 Enzyme 7.5E-05 0.496 0.885
GGT2 P36268 gamma-glutamyltransferase 2 1.3E-04 0.513 0.846
GGTLC1 Q9BX51 gamma-glutamyltransferase light chain 1 Enzyme 3.3E-05 0.559 0.731
GGTLC3 B5MD39 gamma-glutamyltransferase light chain family member 3 0.513 0.846
GGTLC4P gamma-glutamyltransferase light chain 4 pseudogene 0.513 0.846
GGTLC5P gamma-glutamyltransferase light chain 5 pseudogene 0.513 0.846
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
GSTA1 P08263 glutathione S-transferase alpha 1 1.7E-06 0.561 0.731
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808