Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885