Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
HLA-B | P01889 | major histocompatibility complex, class I, B | 3.9E-05 | 0.379 | 0.885 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
MBL2 | P11226 | mannose binding lectin 2 | Receptor | 2.7E-03 | 0.390 | 0.846 |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
AHR | P35869 | aryl hydrocarbon receptor | Transcription factor | 1.00 | 0.410 | 0.923 |
STAT1 | P42224 | signal transducer and activator of transcription 1 | Nucleic acid binding | 1.00 | 0.399 | 0.885 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
PON1 | P27169 | paraoxonase 1 | 9.8E-11 | 0.409 | 0.885 | |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
INSR | P06213 | insulin receptor | Kinase | 3.6E-05 | 0.432 | 0.846 |
WT1 | P19544 | WT1 transcription factor | Nucleic acid binding | 1.00 | 0.422 | 0.808 |
FLT1 | P17948 | fms related receptor tyrosine kinase 1 | Kinase | 1.00 | 0.419 | 0.846 |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
XRCC1 | P18887 | X-ray repair cross complementing 1 | 6.3E-09 | 0.421 | 0.923 | |
HMGA2 | P52926 | high mobility group AT-hook 2 | Nucleic acid binding | 0.87 | 0.429 | 0.808 |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
TET2 | Q6N021 | tet methylcytosine dioxygenase 2 | 4.3E-54 | 0.458 | 0.808 | |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
RB1 | P06400 | RB transcriptional corepressor 1 | Nucleic acid binding | 1.00 | 0.444 | 0.885 |