Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885
FLNA P21333 filamin A 1.00 0.419 0.846
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
NF2 P35240 neurofibromin 2 1.00 0.468 0.885