Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
NOS1 | P29475 | nitric oxide synthase 1 | 1.00 | 0.408 | 0.885 | |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
WNK1 | Q9H4A3 | WNK lysine deficient protein kinase 1 | Kinase | 1.00 | 0.416 | 0.846 |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
NOTCH2 | Q04721 | notch receptor 2 | 1.00 | 0.441 | 0.808 | |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
ARID1A | O14497 | AT-rich interaction domain 1A | 1.00 | 0.455 | 0.846 | |
RB1 | P06400 | RB transcriptional corepressor 1 | Nucleic acid binding | 1.00 | 0.444 | 0.885 |
BRD4 | O60885 | bromodomain containing 4 | Epigenetic regulator | 1.00 | 0.446 | 0.885 |
CACNA1A | O00555 | calcium voltage-gated channel subunit alpha1 A | Ion channel | 1.00 | 0.489 | 0.769 |
KMT2D | O14686 | lysine methyltransferase 2D | 1.00 | 0.465 | 0.808 | |
NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 |