Disease: Intellectual Disability
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
UPF2 Q9HAU5 UPF2 regulator of nonsense mediated mRNA decay Enzyme 1.00 1.000 0.038
TANC1 Q9C0D5 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2.2E-05 0.736 0.115
TSEN15 Q8WW01 tRNA splicing endonuclease subunit 15 0.28 0.769 0.115
TANC2 Q9HCD6 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1.00 0.861 0.154
FILIP1 Q7Z7B0 filamin A interacting protein 1 2.6E-10 0.861 0.154
AGAP1 Q9UPQ3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 1.00 0.839 0.154
EPB41L1 Q9H4G0 erythrocyte membrane protein band 4.1 like 1 0.88 0.839 0.192
ZNF142 P52746 zinc finger protein 142 Transcription factor 4.8E-16 0.861 0.192
SOBP A7XYQ1 sine oculis binding protein homolog 1.00 0.839 0.192
MOCS1 Q9NZB8 molybdenum cofactor synthesis 1 9.1E-07 0.743 0.231
CADPS2 Q86UW7 calcium dependent secretion activator 2 Calcium-binding protein 0.37 0.716 0.231
RALGAPA1 Q6GYQ0 Ral GTPase activating protein catalytic subunit alpha 1 Enzyme modulator 1.00 0.861 0.231
PDE6A P16499 phosphodiesterase 6A 6.6E-25 0.691 0.269
CLASP2 O75122 cytoplasmic linker associated protein 2 Cellular structure 1.00 0.792 0.269
NPAS3 Q8IXF0 neuronal PAS domain protein 3 Transcription factor 1.00 0.729 0.269
ASTN1 O14525 astrotactin 1 1.00 0.736 0.308
PRKG2 Q13237 protein kinase cGMP-dependent 2 Kinase 0.65 0.705 0.308
PITRM1 Q5JRX3 pitrilysin metallopeptidase 1 Enzyme 5.9E-21 0.821 0.308
KIZ Q2M2Z5 kizuna centrosomal protein 0.722 0.308
ZC3H14 Q6PJT7 zinc finger CCCH-type containing 14 0.88 0.691 0.308
PIGC Q92535 phosphatidylinositol glycan anchor biosynthesis class C Enzyme 5.5E-03 0.691 0.346
DHX38 Q92620 DEAH-box helicase 38 Enzyme 2.1E-12 0.711 0.346
CWC27 Q6UX04 CWC27 spliceosome associated cyclophilin Enzyme 4.6E-07 0.722 0.346
TSEN34 Q9BSV6 tRNA splicing endonuclease subunit 34 Enzyme 0.36 0.722 0.346
DDX6 P26196 DEAD-box helicase 6 1.00 0.663 0.385