Disease: Diabetes Mellitus, Non-Insulin-Dependent
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
ELN P15502 elastin 2.1E-14 0.415 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923