Disease: bone destruction
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BTF3P11 basic transcription factor 3 pseudogene 11 0.519 0.731
OAS3 Q9Y6K5 2'-5'-oligoadenylate synthetase 3 Enzyme 2.0E-33 0.608 0.615
PMEL P40967 premelanosome protein Signaling 3.1E-18 0.531 0.769
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
SH3BP2 P78314 SH3 domain binding protein 2 1.2E-11 0.623 0.654
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
IL20 Q9NYY1 interleukin 20 1.3E-06 0.556 0.769
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
IPP Q9Y573 intracisternal A particle-promoted polypeptide 2.1E-05 0.760 0.308
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CTSK P43235 cathepsin K Enzyme 3.1E-05 0.497 0.808
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
IL11 P20809 interleukin 11 3.2E-04 0.481 0.808
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885