Disease: Hypogammaglobulinemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731
BLNK Q8WV28 B cell linker Signaling 0.61 0.603 0.731
CD19 P15391 CD19 molecule 0.90 0.430 0.885
CD79A P11912 CD79a molecule Receptor 0.69 0.536 0.731
CD79B P40259 CD79b molecule Receptor 0.92 0.576 0.577
CD81 P60033 CD81 molecule 0.92 0.555 0.846
CR2 P20023 complement C3d receptor 2 4.7E-19 0.556 0.654
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731
IGHM P01871 immunoglobulin heavy constant mu 0.644 0.654
IGLL1 P15814 immunoglobulin lambda like polypeptide 1 1.4E-02 0.678 0.538
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
LRBA P50851 LPS responsive beige-like anchor protein 7.2E-12 0.608 0.692
LRRC8A Q8IWT6 leucine rich repeat containing 8 VRAC subunit A 0.94 0.644 0.692
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
NFKB2 Q00653 nuclear factor kappa B subunit 2 Transcription factor 1.00 0.509 0.808
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TCF3 P15923 transcription factor 3 Transcription factor 2.6E-02 0.476 0.846