Disease: Pauci-immune Glomerulonephritis associated with Granulomatosis with Polyangiitis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CEL P19835 carboxyl ester lipase 1.5E-06 0.514 0.808
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
ELANE P08246 elastase, neutrophil expressed Enzyme 1.2E-03 0.447 0.846
FLNB O75369 filamin B 6.1E-10 0.458 0.923
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MMP8 P22894 matrix metallopeptidase 8 Enzyme 1.1E-24 0.488 0.808
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
NXF1 Q9UBU9 nuclear RNA export factor 1 Nucleic acid binding 0.98 0.531 0.885
PARP9 Q8IXQ6 poly(ADP-ribose) polymerase family member 9 5.0E-09 0.554 0.808
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
PRTN3 P24158 proteinase 3 Enzyme 3.8E-05 0.503 0.808
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
SEC14L2 O76054 SEC14 like lipid binding 2 2.9E-08 0.494 0.885
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
SLC27A5 Q9Y2P5 solute carrier family 27 member 5 Transporter 8.4E-15 0.563 0.769
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
USO1 O60763 USO1 vesicle transport factor Transporter 0.33 0.522 0.885