Disease: Renal fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
ANPEP P15144 alanyl aminopeptidase, membrane Enzyme 3.7E-09 0.462 0.769
AZGP1 P25311 alpha-2-glycoprotein 1, zinc-binding 4.2E-06 0.566 0.769
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CXCL16 Q9H2A7 C-X-C motif chemokine ligand 16 Signaling 3.5E-05 0.502 0.769
DNER Q8NFT8 delta/notch like EGF repeat containing 0.19 0.493 0.769
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
EIF4EBP1 Q13541 eukaryotic translation initiation factor 4E binding protein 1 Nucleic acid binding 0.21 0.494 0.885
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FGF23 Q9GZV9 fibroblast growth factor 23 Signaling 3.1E-02 0.460 0.731
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
GCG P01275 glucagon 3.5E-02 0.431 0.885
GDF11 O95390 growth differentiation factor 11 Signaling 0.98 0.584 0.692
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808