Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
SPP1 | P10451 | secreted phosphoprotein 1 | 2.1E-06 | 0.353 | 0.885 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
IL18 | Q14116 | interleukin 18 | 3.1E-02 | 0.365 | 0.923 | |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
EPO | P01588 | erythropoietin | 1.1E-02 | 0.381 | 0.885 | |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
TIMP1 | P01033 | TIMP metallopeptidase inhibitor 1 | Enzyme modulator | 0.50 | 0.380 | 0.885 |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
CASR | P41180 | calcium sensing receptor | G-protein coupled receptor | 4.7E-02 | 0.410 | 0.846 |
LCN2 | P80188 | lipocalin 2 | Enzyme | 1.1E-09 | 0.405 | 0.885 |
PDGFRB | P09619 | platelet derived growth factor receptor beta | Kinase | 0.90 | 0.416 | 0.846 |
COL1A1 | P02452 | collagen type I alpha 1 chain | 1.00 | 0.430 | 0.808 | |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
TIMP2 | P16035 | TIMP metallopeptidase inhibitor 2 | Enzyme modulator | 0.79 | 0.425 | 0.846 |
ITGB2 | P05107 | integrin subunit beta 2 | Receptor | 5.1E-15 | 0.444 | 0.923 |
KL | Q9UEF7 | klotho | Enzyme | 2.2E-04 | 0.448 | 0.769 |
COL18A1 | P39060 | collagen type XVIII alpha 1 chain | 1.7E-10 | 0.449 | 0.808 |