Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
PPP2R1A | P30153 | protein phosphatase 2 scaffold subunit Aalpha | Enzyme | 0.98 | 0.588 | 0.577 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
XPO1 | O14980 | exportin 1 | Receptor | 1.00 | 0.504 | 0.692 |
CNOT9 | Q92600 | CCR4-NOT transcription complex subunit 9 | 0.99 | 0.769 | 0.192 | |
SPOP | O43791 | speckle type BTB/POZ protein | 1.00 | 0.597 | 0.500 |