Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
FANCA | O15360 | FA complementation group A | 1.6E-68 | 0.505 | 0.731 | |
AURKA | O14965 | aurora kinase A | Kinase | 0.87 | 0.475 | 0.731 |
HDAC2 | Q92769 | histone deacetylase 2 | Epigenetic regulator | 1.00 | 0.476 | 0.846 |
MAD1L1 | Q9Y6D9 | mitotic arrest deficient 1 like 1 | 6.8E-16 | 0.570 | 0.731 | |
FOXA1 | P55317 | forkhead box A1 | Transcription factor | 0.22 | 0.522 | 0.731 |
KLF6 | Q99612 | Kruppel like factor 6 | Nucleic acid binding | 0.98 | 0.501 | 0.846 |
AXIN1 | O15169 | axin 1 | 0.41 | 0.559 | 0.577 | |
EPHB2 | P29323 | EPH receptor B2 | Kinase | 1.00 | 0.374 | 0.846 |
SPOP | O43791 | speckle type BTB/POZ protein | 1.00 | 0.597 | 0.500 |