Disease: Tumor Initiation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DPT Q07507 dermatopontin Extracellular structure 4.3E-06 0.641 0.654
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923