Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AIC | Aicardi syndrome | 0.729 | 0.462 | |||
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BCS1L | Q9Y276 | BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone | 4.7E-13 | 0.534 | 0.808 | |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
BRIP1 | Q9BX63 | BRCA1 interacting protein C-terminal helicase 1 | Enzyme | 6.2E-17 | 0.507 | 0.731 |
CA9 | Q16790 | carbonic anhydrase 9 | 1.3E-09 | 0.483 | 0.731 | |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
CHEK1 | O14757 | checkpoint kinase 1 | Kinase | 3.1E-08 | 0.492 | 0.808 |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
EIF4E | P06730 | eukaryotic translation initiation factor 4E | Nucleic acid binding | 0.94 | 0.448 | 0.846 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
GATA3 | P23771 | GATA binding protein 3 | 0.90 | 0.415 | 0.846 | |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
MIB1 | Q86YT6 | mindbomb E3 ubiquitin protein ligase 1 | Enzyme | 3.4E-88 | 0.438 | 0.769 |
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |