Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
ARID1A | O14497 | AT-rich interaction domain 1A | 1.00 | 0.455 | 0.846 | |
L1CAM | P32004 | L1 cell adhesion molecule | 1.00 | 0.475 | 0.769 | |
HDAC6 | Q9UBN7 | histone deacetylase 6 | Epigenetic regulator | 1.00 | 0.465 | 0.846 |
HDAC4 | P56524 | histone deacetylase 4 | Epigenetic regulator | 1.00 | 0.484 | 0.885 |
FASN | P49327 | fatty acid synthase | Enzyme | 1.00 | 0.474 | 0.846 |
KDM6A | O15550 | lysine demethylase 6A | Epigenetic regulator | 1.00 | 0.498 | 0.769 |
STAG2 | Q8N3U4 | stromal antigen 2 | Nucleic acid binding | 1.00 | 0.568 | 0.731 |
HDAC5 | Q9UQL6 | histone deacetylase 5 | Epigenetic regulator | 1.00 | 0.552 | 0.769 |
KMT2C | Q8NEZ4 | lysine methyltransferase 2C | 1.00 | 0.558 | 0.692 | |
NCOR1 | O75376 | nuclear receptor corepressor 1 | Transcription factor | 1.00 | 0.597 | 0.731 |
EIF3A | Q14152 | eukaryotic translation initiation factor 3 subunit A | Nucleic acid binding | 1.00 | 0.592 | 0.769 |
EIF4G2 | P78344 | eukaryotic translation initiation factor 4 gamma 2 | Nucleic acid binding | 1.00 | 0.593 | 0.692 |